Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 2/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899668 | 0.81 | GSK3B (0.44) | GSK3BDYRK1ASCN9A | |
| SCHEMBL30899670 | 0.80 | BRD9 (0.39) | GSK3BDYRK1AKLKB1CA12CA1 | |
| SCHEMBL30899678 | 0.73 | KDM4E (0.38) | GSK3BDYRK1AMEN1KMT2AATM | |
| SCHEMBL30899671 | 0.73 | PIM1 (0.39) | GSK3BDYRK1ASCN9A | |
| SCHEMBL31406223 | 0.71 | PDE1A (0.43) | PDE1APDE1BPDE1CNPC1RAB9A | |
| SCHEMBL28006554 | 0.71 | GSK3B (0.45) | GSK3BDYRK1A | |
| SCHEMBL9887468 | 0.70 | KLKB1 (0.44) | GSK3BDYRK1AKLKB1CA12CA1 | |
| SCHEMBL17598745 | 0.69 | GSK3B (0.39) | GSK3BDYRK1AKLKB1CA1LCK | |
| SCHEMBL27731447 | 0.68 | GSK3B (0.39) | GSK3BDYRK1AKLKB1CA1LCK | |
| SCHEMBL25833918 | 0.68 | CNR2 (0.38) | GSK3BDYRK1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119562952-A | KIF18A inhibitors | 山东轩竹医药科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2024067465-A1 | KIF18A INHIBITOR | 山东轩竹医药科技有限公司 | 2024-04-04 | — | — | WO | disclosed |