Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | LATS1 | O95835 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1978195 | 0.85 | PGK1 (0.39) | PDE10ASIRT2 | |
| SCHEMBL30657526 | 0.85 | PGK1 (0.39) | PDE10ASIRT2 | |
| SCHEMBL995459 | 0.85 | APP (0.50) | APPPDE5ALATS1KDM4ENPSR1 | |
| SCHEMBL15060834 | 0.82 | TLR7 (0.39) | APPKDM4ENPSR1L3MBTL1MAPT | |
| SCHEMBL11361897 | 0.82 | PLAU (0.43) | KDM4EALDH1A1HPGDHSD17B10SLC2A1 | |
| SCHEMBL11354730 | 0.80 | SLC2A1 (0.49) | TLR8MAPTSLC2A1 | |
| SCHEMBL739251 | 0.79 | KMT2A (0.47) | KDM4ENPSR1TLR8MAPTTLR7 | |
| SCHEMBL14940822 | 0.77 | NUDT1 (0.45) | LATS1MAPTLATS2SIRT2 | |
| SCHEMBL23181666 | 0.76 | APP (0.45) | APPPDE5ALATS1KDM4ETLR8 | |
| SCHEMBL12046243 | 0.76 | APP (0.45) | APPPDE5ALATS1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119562952-A | KIF18A inhibitors | 山东轩竹医药科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2024067465-A1 | KIF18A INHIBITOR | 山东轩竹医药科技有限公司 | 2024-04-04 | — | — | WO | disclosed |