Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.31 |
| ▸ | PNMT | P11086 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21648919 | 1.00 | MAPK1 (0.34) | MAPK1ALDH1A1TDP1L3MBTL1EPHX2 | |
| SCHEMBL20309114 | 0.84 | TRPV1 (0.32) | EPHX2TRPV1SLC1A5PNMT | |
| SCHEMBL19033849 | 0.78 | EPHX2 (0.50) | EPHX2PDE2ATRPV1SLC1A5 | |
| SCHEMBL261397 | 0.78 | PKM (0.47) | MAPK1ALDH1A1TDP1L3MBTL1EPHX2 | |
| SCHEMBL24731505 | 0.76 | MAPK1 (0.34) | MAPK1ALDH1A1TDP1L3MBTL1EPHX2 | |
| SCHEMBL17420405 | 0.76 | SCN5A (0.41) | EPHX2PDE2ATRPV1SLC1A5 | |
| SCHEMBL508527 | 0.76 | SLC1A5 (0.47) | SLC1A5 | |
| SCHEMBL16951248 | 0.76 | MBOAT4 (0.36) | MAPK1ALDH1A1TDP1L3MBTL1EPHX2 | |
| SCHEMBL263399 | 0.76 | EPHX2 (0.38) | MAPK1ALDH1A1TDP1L3MBTL1EPHX2 | |
| SCHEMBL263489 | 0.76 | MBOAT4 (0.39) | MAPK1ALDH1A1TDP1L3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658987-A | Compounds as PLK1 inhibitors, and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-03-08 | — | — | CN | disclosed |