⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25527250 | 0.84 | TSHR (0.31) | — | |
| SCHEMBL21849290 | 0.67 | MAPK14 (0.38) | — | |
| SCHEMBL24655988 | 0.66 | CHRM5 (0.37) | — | |
| SCHEMBL15306539 | 0.66 | PIK3CG (0.54) | — | |
| SCHEMBL24654976 | 0.66 | BRD4 (0.31) | — | |
| SCHEMBL21894547 | 0.65 | PIK3CG (0.33) | — | |
| SCHEMBL6935092 | 0.65 | BTK (0.35) | — | |
| SCHEMBL15004610 | 0.65 | CHRM5 (0.38) | — | |
| SCHEMBL29749600 | 0.64 | ADRA1A (0.31) | — | |
| SCHEMBL25101269 | 0.62 | AXL (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204009-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2024-05-07 | — | — | CN | disclosed |