SCHEMBL21894547

SCHEMBL21894547

Cc1nn2ccnc(C)c2c1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.33
MTNR1A P48039 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24655984 0.76 PIK3CG (0.30) PIK3CG
SCHEMBL21893426 0.76 CHRM5 (0.35)
SCHEMBL24588920 0.75 ADRA1A (0.32)
SCHEMBL21894380 0.74 POLB (0.40)
Potassium Ion SCHEMBL21818488 0.71 POLB (0.30)
SCHEMBL19939404 0.70 ALDH1A1 (0.37)
SCHEMBL21818303 0.68 PDE4D (0.48)
SCHEMBL18798825 0.65 DYRK1A (0.36) PIK3CG
SCHEMBL30900596 0.65
SCHEMBL24655988 0.64 CHRM5 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020065613-A1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2020-04-02 WO disclosed