Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 11/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22437082 | 1.00 | LOXL2 (0.58) | LOXL2CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL31506438 | 0.79 | LOXL2 (0.60) | LOXL2CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL26663329 | 0.79 | ALDH1A1 (0.38) | LOXL2CYP1A2CYP2C19TSHRMAPT | |
| SCHEMBL12755537 | 0.78 | LOXL2 (0.58) | LOXL2CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4595436 | 0.78 | LOXL2 (0.63) | LOXL2CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL30270572 | 0.74 | CYP3A4 (0.53) | LOXL2CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2894523 | 0.74 | CYP3A4 (0.46) | LOXL2CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9521235 | 0.74 | CYP3A4 (0.58) | LOXL2CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11015868 | 0.74 | LOXL2 (0.71) | LOXL2CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL18049309 | 0.74 | LOXL2 (1.00) | LOXL2CYP3A4CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204009-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2024-05-07 | — | — | CN | disclosed |