Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137883 | 0.87 | TAAR1 (0.54) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| SCHEMBL13889581 | 0.79 | ESR1 (0.54) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| SCHEMBL28279595 | 0.77 | TP53 (0.39) | TAAR1SLC6A2LMNATSHRALDH1A1 | |
| SCHEMBL28864140 | 0.75 | LOXL2 (0.46) | TAAR1SLC6A2HRH3 | |
| SCHEMBL24618316 | 0.75 | TAAR1 (0.47) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| SCHEMBL17151110 | 0.75 | TAAR1 (0.47) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| SCHEMBL10420307 | 0.75 | TAAR1 (0.47) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| SCHEMBL9467793 | 0.75 | TAAR1 (0.75) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| SCHEMBL30901114 | 0.75 | TAAR1 (0.47) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| SCHEMBL13151044 | 0.72 | TAAR1 (0.47) | TAAR1SLC6A2LMNACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986139-A | Synthesis method of 1- (biphenyl-4-yl) -2-methyl-2-aminopropane-1-ketone | 深圳有为技术控股集团有限公司 | 2024-05-07 | — | — | CN | disclosed |