SCHEMBL6137883

SCHEMBL6137883

CN(C)C(C)(C)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.54
SLC6A2 P23975 1/20 0.54
LMNA P02545 2/20 0.50
CYP2D6 P10635 2/20 0.50
TSHR P16473 2/20 0.47
CYP2C19 P33261 2/20 0.47
HIF1A Q16665 2/20 0.47
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47
SCN1A P35498 1/20 0.47
KMT2A Q03164 1/20 0.47
SCN2A Q99250 1/20 0.47
SCN3A Q9NY46 1/20 0.47
ALDH1A1 P00352 1/20 0.46
NPY5R Q15761 1/20 0.44
TRPA1 O75762 1/20 0.44
AOC3 Q16853 2/20 0.43
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30901121 0.87 TAAR1 (0.53) TAAR1SLC6A2LMNACYP2D6TSHR
SCHEMBL13151044 0.83 TAAR1 (0.47) TAAR1SLC6A2LMNACYP2D6TSHR
SCHEMBL28019453 0.82 TAAR1 (0.50) TAAR1SLC6A2LMNACYP2D6TSHR
SCHEMBL28279595 0.79 TP53 (0.39) TAAR1SLC6A2LMNATSHRALDH1A1
SCHEMBL31468672 0.79 LMNA (0.48) TAAR1SLC6A2LMNACYP2D6TSHR
SCHEMBL27661323 0.77 TAAR1 (0.50) TAAR1SLC6A2LMNACYP2D6TSHR
SCHEMBL5865899 0.77 TAAR1 (0.50) TAAR1SLC6A2LMNACYP2D6TSHR
SCHEMBL27990215 0.77 TAAR1 (0.50) TAAR1SLC6A2LMNACYP2D6TSHR
SCHEMBL28864140 0.77 LOXL2 (0.46) TAAR1SLC6A2
SCHEMBL30636152 0.77 TAAR1 (0.45) TAAR1SLC6A2LMNACYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110412839-A Positively charged toner, image forming apparatus and image forming method KYOCERA DOCUMENT SOLUTIONS INC 2019-11-05 CN disclosed
EP-1172388-B1 Low-density, water blown polyurethane foams for energy-absorbing applications BAYER AG (US) 2005-08-24 EP disclosed