Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1240376 | 1.00 | KDM4E (0.49) | KDM4ENQO2GPR3ERCC1FEN1 | |
| SCHEMBL20670034 | 0.82 | GPR3 (0.54) | KDM4ENQO2GPR3ERCC1FEN1 | |
| SCHEMBL22035485 | 0.79 | EGFR (0.40) | ALDH1A1LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL28973482 | 0.78 | ALDH1A1 (0.55) | KDM4ENQO2GPR3ERCC1FEN1 | |
| SCHEMBL19924998 | 0.77 | KMT2A (0.62) | KDM4EGPR3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15876642 | 0.77 | ALDH1A1 (0.50) | KDM4EGPR3ERCC1FEN1ERCC4 | |
| SCHEMBL31018139 | 0.77 | ALDH1A1 (0.50) | KDM4EGPR3ERCC1FEN1ERCC4 | |
| SCHEMBL14448732 | 0.76 | GPR3 (0.56) | KDM4ENQO2GPR3ERCC1FEN1 | |
| SCHEMBL21978883 | 0.76 | ATM (0.43) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL21979007 | 0.76 | ATM (0.50) | KDM4EALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112969700-B | Imidazopyridine derivatives as alpha 4 beta 7 integrin inhibitors | 吉利德科学公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-112996786-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-112969504-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |