Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | PMM2 | O15305 | 3/20 | 0.36 |
| ▸ | PHOSPHO1 | Q8TCT1 | 3/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21979007 | 1.00 | ATM (0.50) | ATMKAT2BTP53POLBTTR | |
| SCHEMBL30901264 | 0.87 | ATM (0.43) | ATMKAT2BTP53POLBPGR | |
| SCHEMBL21978883 | 0.87 | ATM (0.43) | ATMKAT2BTP53POLBPGR | |
| SCHEMBL21978885 | 0.81 | MAT2A (0.46) | TTRALDH1A1LMNAHDAC8 | |
| SCHEMBL30901317 | 0.81 | MAT2A (0.46) | TTRALDH1A1LMNAHDAC8 | |
| SCHEMBL22016182 | 0.78 | ATM (0.48) | ATMKAT2BTP53POLBTTR | |
| SCHEMBL30901263 | 0.76 | KDM4E (0.49) | PGRKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL1240376 | 0.76 | KDM4E (0.49) | PGRKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL22035485 | 0.73 | EGFR (0.40) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL17825042 | 0.73 | ATM (0.56) | ATMPKMKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112969504-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |