Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 11/20 | 0.49 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865925 | 1.00 | KDM4E (0.61) | KDM4ENQO2HSD17B10KIF11AR | |
| SCHEMBL27579314 | 0.80 | BACE1 (0.39) | KDM4ENQO2HSD17B10KIF11AR | |
| SCHEMBL21957297 | 0.79 | AR (0.50) | ARATMPGR | |
| SCHEMBL27518959 | 0.79 | ALDH1A1 (0.42) | KDM4ENQO2HSD17B10KIF11AR | |
| SCHEMBL31331699 | 0.78 | AR (0.53) | KDM4EHSD17B10ARATMPGR | |
| SCHEMBL6077653 | 0.78 | AR (0.52) | KDM4EHSD17B10ARATMPGR | |
| SCHEMBL21978549 | 0.78 | AR (0.49) | ARPGR | |
| SCHEMBL5865904 | 0.77 | PARG (0.47) | ARPGRMAPT | |
| SCHEMBL6023005 | 0.77 | PIK3CG (0.57) | KIF11ARPGR | |
| SCHEMBL5865893 | 0.77 | PARG (0.50) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462635-A | Quinoline derivatives as alpha 4 beta 7 integrin inhibitors | 吉利德科学公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-112969687-B | Quinoline derivatives as a4 b 7 integrin inhibitors | 吉利德科学公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-112969504-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |