SCHEMBL3090240

SCHEMBL3090240

CC(C)CCc1ccc(NNc2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIA4 P48058 1/20 0.46
NR1H4 Q96RI1 3/20 0.42
KCNH2 Q12809 1/20 0.41
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
CNR1 P21554 2/20 0.40
TRPV1 Q8NER1 1/20 0.39
ESRRG P62508 2/20 0.39
CNR2 P34972 1/20 0.39
ESRRB O95718 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
SIGMAR1 Q99720 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL582269 0.81 ESRRG (0.51) GRIA4KCNH2TP53TSHRESRRG
SCHEMBL6948447 0.78 KCNH2 (0.55) GRIA4NR1H4KCNH2TP53TSHR
SCHEMBL582268 0.77 KCNH2 (0.42) GRIA4NR1H4KCNH2TP53TSHR
SCHEMBL31212779 0.77 TSHR (0.52) NR1H4TSHRTRPV1CA1CA2
SCHEMBL31212783 0.77 TSHR (0.52) NR1H4TSHRTRPV1CA1CA2
SCHEMBL1660004 0.74 GRIA4 (0.47) GRIA4KCNH2TP53TSHRESRRG
SCHEMBL8080450 0.74 HTT (0.41) TSHR
SCHEMBL17620454 0.74 MAPT (0.39) TSHR
SCHEMBL46497 0.73 KDM4E (0.53) GRIA4NR1H4TP53TSHR
SCHEMBL17898163 0.73 GRIA4 (0.46) GRIA4KCNH2TP53TSHRESRRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100263262-A1 Unleaded aviation gasoline EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-10-21 US disclosed