SCHEMBL582268

SCHEMBL582268

CC(C)CCc1ccc(N(N)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.42
GRIA4 P48058 1/20 0.41
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
LMNA P02545 1/20 0.38
EPHX1 P07099 1/20 0.36
AOC3 Q16853 2/20 0.36
SIGMAR1 Q99720 4/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
ADRA1D P25100 1/20 0.36
HTR1D P28221 1/20 0.36
HTR1B P28222 1/20 0.36
ADRA1A P35348 1/20 0.36
ADRA1B P35368 1/20 0.36
ESRRG P62508 2/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
NR1H4 Q96RI1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL582269 0.81 ESRRG (0.51) KCNH2GRIA4TP53TSHREPHX1
SCHEMBL17461052 0.78 TSHR (0.48) KCNH2TSHRLMNACA1CA2
SCHEMBL3090240 0.77 GRIA4 (0.46) KCNH2GRIA4TP53TSHRSIGMAR1
SCHEMBL6948447 0.75 KCNH2 (0.55) KCNH2GRIA4TP53TSHRLMNA
SCHEMBL21153502 0.73 HRH3 (0.35) KCNH2TSHRLMNAAOC3
SCHEMBL1660004 0.72 GRIA4 (0.47) KCNH2GRIA4TP53TSHRLMNA
SCHEMBL8080450 0.72 HTT (0.41) TSHRAOC3
Hydrochloric Acid SCHEMBL9734626 0.71 KCNH2 (0.50) KCNH2GRIA4TP53TSHRLMNA
SCHEMBL22086280 0.71 RAB9A (0.45) TSHRLMNANR1H4
SCHEMBL13886433 0.71 ALDH1A1 (0.54) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2417230-B1 UNLEADED AVIATION GASOLINE EXXONMOBIL RES & ENG CO (US) 2016-05-11 EP disclosed
EP-2417230-A1 UNLEADED AVIATION GASOLINE ExxonMobil Research and Engineering Company (US) 2012-02-15 EP disclosed
WO-2010118408-A1 UNLEADED AVIATION GASOLINE EXXONMOBIL RESEARCH & ENGINEERING COMPANY (US) 2010-10-14 WO disclosed