Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29206806 | 1.00 | FAAH (0.42) | FAAHCES1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL29206823 | 0.87 | FAAH (0.42) | FAAHCES1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL30904776 | 0.87 | FAAH (0.42) | FAAHCES1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL30904780 | 0.81 | FAAH (0.43) | FAAHCES1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL29206815 | 0.75 | ACP1 (0.46) | FAAHCES1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL30904777 | 0.75 | ACP1 (0.46) | FAAHCES1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL23995211 | 0.73 | PLAU (0.41) | CYP1A2QPCTQPCTLGABRG2GABRB3 | |
| SCHEMBL30904786 | 0.71 | FAAH (0.44) | FAAHCES1SMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL30904781 | 0.71 | CYP1A2 (0.47) | FAAHCES1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL29206805 | 0.71 | CYP1A2 (0.47) | FAAHCES1ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005615-A | Pyridazine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |