Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 7/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29206815 | 1.00 | ACP1 (0.46) | ACP1FAAHCES1PTGDRKDM4E | |
| SCHEMBL29206792 | 0.90 | ACP1 (0.41) | ACP1FAAHCES1PTGDRKDM4E | |
| SCHEMBL30904773 | 0.90 | ACP1 (0.41) | ACP1FAAHCES1PTGDRKDM4E | |
| SCHEMBL30904786 | 0.86 | FAAH (0.44) | ACP1FAAHCES1PTGDRKDM4E | |
| SCHEMBL29206852 | 0.86 | FAAH (0.44) | ACP1FAAHCES1PTGDRKDM4E | |
| SCHEMBL29206806 | 0.75 | FAAH (0.42) | ACP1FAAHCES1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30904776 | 0.75 | FAAH (0.42) | ACP1FAAHCES1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29206823 | 0.75 | FAAH (0.42) | ACP1FAAHCES1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30904787 | 0.75 | FAAH (0.42) | ACP1FAAHCES1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30904780 | 0.75 | FAAH (0.43) | ACP1FAAHCES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005615-A | Pyridazine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |