SCHEMBL30905887

SCHEMBL30905887

N#Cc1cccc(-c2ccc(=O)n(Cc3cccc(-c4ncc(OCC5CCN(C(=O)CCl)CC5)cn4)c3)n2)c1

nearest known ligand 0.80

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MET P08581 17/20 0.80
▸ NQO2 P16083 1/20 0.80
▸ CHRM4 P08173 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2480684 0.93 MET (0.82) METNQO2
SCHEMBL29222978 0.89 MET (0.74) METNQO2
Tepotinib SCHEMBL1296895 0.89 MET (1.00) METNQO2
Tepotinib SCHEMBL29379106 0.89 MET (1.00) METNQO2
SCHEMBL3084089 0.89 MET (0.78) METNQO2
SCHEMBL29223103 0.88 MET (0.80) METNQO2CHRM4
SCHEMBL31690377 0.88 MET (0.80) METNQO2CHRM4
SCHEMBL2480686 0.88 MET (0.80) METNQO2CHRM4
Tepotinib SCHEMBL1295616 0.88 MET (0.98) METNQO2
Tepotinib SCHEMBL30259391 0.88 MET (0.98) METNQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4624466-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 — — EP disclosed
WO-2024112119-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 — — WO disclosed
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