Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909150 | 0.93 | KDM4E (0.41) | KDM4EMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL31054164 | 0.88 | MAPT (0.48) | KDM4EMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL27924016 | 0.86 | KDM4E (0.44) | KDM4EMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL30177551 | 0.86 | ALDH1A1 (0.50) | KDM4EMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL27867480 | 0.84 | ALDH1A1 (0.41) | KDM4EHSD17B10ALDH1A1TSHRSLC16A3 | |
| SCHEMBL25383768 | 0.82 | F7 (0.56) | KDM4EMAPTHSD17B10MEN1NR1I2 | |
| SCHEMBL8366893 | 0.81 | MAPT (0.42) | KDM4EMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL29690496 | 0.81 | MAPT (0.42) | KDM4EMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL1004461 | 0.80 | LMNA (0.58) | MAPTALDH1A1TSHRMEN1NR1I2 | |
| SCHEMBL1004554 | 0.80 | LMNA (0.58) | MAPTALDH1A1TSHRMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11981929-B2 | Use of small molecules to enhance MAFA expression in pancreatic endocrine cells | JANSSEN BIOTECH, INC. (US) | 2024-05-14 | — | — | US | disclosed |