Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519732 | 0.80 | NPC1 (0.44) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL29354715 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL19291 | 0.80 | NPC1 (0.44) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL6890133 | 0.79 | NPC1 (0.42) | ALDH1A1HPGDMAPTGLAACHE | |
| Methane SCHEMBL11523432 | 0.79 | NPC1 (0.42) | ALDH1A1HPGDMAPTGLAACHE | |
| Hydrochloric Acid SCHEMBL27346450 | 0.79 | NPC1 (0.42) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL4674985 | 0.78 | NPC1 (0.41) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL6748828 | 0.76 | ALDH1A1 (0.37) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL5177973 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HPGDMAPTGLAACHE | |
| Anthraquinone SCHEMBL11078992 | 0.75 | NPC1 (0.54) | ALDH1A1HPGDMAPTGLAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709853-A1 | METHODS OF PREVENTING ON-TARGET GENOTOXICITY INDUCED BY NUCLEASES | Institut National de la Santé et de la Recherche Médicale (FR) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024235844-A1 | METHODS OF PREVENTING ON-TARGET GENOTOXICITY INDUCED BY NUCLEASES | Institut National de la Santé et de la Recherche Médicale (FR) | 2024-11-21 | — | — | WO | disclosed |
| US-11981929-B2 | Use of small molecules to enhance MAFA expression in pancreatic endocrine cells | JANSSEN BIOTECH, INC. (US) | 2024-05-14 | — | — | US | disclosed |