Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29641041 | 0.96 | MAPT (0.50) | MAPTLMNAALDH1A1PDK2NAMPT | |
| SCHEMBL21933316 | 0.96 | MAPT (0.50) | MAPTLMNAALDH1A1PDK2NAMPT | |
| SCHEMBL20046718 | 0.87 | MAPT (0.50) | MAPTLMNAALDH1A1PDK2NAMPT | |
| SCHEMBL30678672 | 0.85 | MAPT (0.52) | MAPTLMNAALDH1A1PDK2NAMPT | |
| SCHEMBL20231910 | 0.85 | MAPT (0.52) | MAPTLMNAALDH1A1PDK2NAMPT | |
| SCHEMBL31707418 | 0.84 | GPR119 (0.48) | ALDH1A1NR1H2NR1H3GPR119 | |
| SCHEMBL25202645 | 0.84 | CYP11B2 (0.41) | MAPTLMNAALDH1A1PDK2NR1H2 | |
| SCHEMBL22454337 | 0.84 | CYP3A4 (0.47) | ALDH1A1PDK2SMN1; SMN2NR1H2NR1H3 | |
| SCHEMBL30423051 | 0.84 | CYP11B2 (0.41) | MAPTLMNAALDH1A1PDK2NR1H2 | |
| SCHEMBL24951416 | 0.84 | MAPT (0.51) | MAPTLMNAALDH1A1PDK2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598905-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | University of Florida Research Foundation, Incorporated (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024077023-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-11 | — | — | WO | disclosed |