Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 4/20 | 0.47 |
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.46 |
| ▸ | GSPT1 | P15170 | 3/20 | 0.43 |
| ▸ | SALL4 | Q9UJQ4 | 2/20 | 0.43 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25933315 | 1.00 | CRBN (0.52) | CRBNCSNK1A1IKZF2GSPT1SALL4 | |
| SCHEMBL20234915 | 0.86 | CRBN (0.53) | CRBNGSPT1IKZF3DDB1 | |
| SCHEMBL22873392 | 0.86 | CRBN (0.53) | CRBNGSPT1IKZF3DDB1 | |
| SCHEMBL30906241 | 0.86 | CRBN (0.47) | CRBNCSNK1A1IKZF2GSPT1IKZF3 | |
| SCHEMBL20231704 | 0.86 | CRBN (0.53) | CRBNCSNK1A1IKZF2GSPT1IKZF3 | |
| SCHEMBL30906237 | 0.85 | CRBN (0.45) | CRBNCSNK1A1IKZF2GSPT1IKZF3 | |
| SCHEMBL30906325 | 0.81 | CRBN (0.54) | CRBNCSNK1A1IKZF2GSPT1IKZF3 | |
| SCHEMBL20231507 | 0.81 | CRBN (0.54) | CRBNCSNK1A1IKZF2GSPT1IKZF3 | |
| SCHEMBL20046704 | 0.81 | CRBN (0.56) | CRBNCSNK1A1IKZF2DDB1 | |
| SCHEMBL31611548 | 0.81 | CRBN (0.56) | CRBNCSNK1A1IKZF2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598905-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | University of Florida Research Foundation, Incorporated (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024077023-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-11 | — | — | WO | disclosed |