SCHEMBL30906241

SCHEMBL30906241

CC(C)(C)OC(=O)N1CC(CN2CC3CC2CN3c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 11/20 0.47
▸ IKZF2 Q9UKS7 6/20 0.42
▸ CSNK1A1 P48729 2/20 0.42
▸ DDB1 Q16531 3/20 0.42
▸ GSPT1 P15170 2/20 0.42
▸ IKZF3 Q9UKT9 1/20 0.42
▸ WIZ O95785 2/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ KCNH2 Q12809 1/20 0.41
▸ IKZF1 Q13422 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30906237 0.94 CRBN (0.45) CRBNIKZF2CSNK1A1DDB1GSPT1
SCHEMBL25933315 0.86 CRBN (0.52) CRBNIKZF2CSNK1A1DDB1GSPT1
SCHEMBL30906248 0.86 CRBN (0.52) CRBNIKZF2CSNK1A1DDB1GSPT1
SCHEMBL20231897 0.84 CRBN (0.53) CRBNIKZF2CSNK1A1DDB1GSPT1
SCHEMBL30906200 0.84 CRBN (0.48) CRBNIKZF2CSNK1A1DDB1
SCHEMBL30906282 0.82 CRBN (0.52) CRBNIKZF2DDB1WIZIKZF1
Trifluoroacetic Acid SCHEMBL30906252 0.82 IKZF2 (0.54) CRBNIKZF2CSNK1A1DDB1GSPT1
Trifluoroacetic Acid SCHEMBL30906217 0.81 IKZF2 (0.55) CRBNIKZF2CSNK1A1DDB1GSPT1
SCHEMBL30942475 0.81 IKZF2 (0.51) CRBNIKZF2CSNK1A1DDB1GSPT1
SCHEMBL27302318 0.81 IKZF2 (0.51) CRBNIKZF2CSNK1A1DDB1GSPT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598905-A2 CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS University of Florida Research Foundation, Incorporated (US) 2025-08-13 — — EP disclosed
WO-2024077023-A2 CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-04-11 — — WO disclosed
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