SCHEMBL30906237

SCHEMBL30906237

CC(C)(C)OC(=O)N1CCC(CN2CC3CC2CN3c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)CC1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 11/20 0.45
▸ IKZF2 Q9UKS7 6/20 0.45
▸ DDB1 Q16531 4/20 0.42
▸ GSPT1 P15170 2/20 0.42
▸ IKZF3 Q9UKT9 1/20 0.42
▸ WIZ O95785 2/20 0.42
▸ ESR1 P03372 1/20 0.42
▸ CSNK1A1 P48729 2/20 0.41
▸ IKZF1 Q13422 1/20 0.41
▸ CYP2C19 P33261 1/20 0.40
▸ KCNH2 Q12809 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30906241 0.94 CRBN (0.47) CRBNIKZF2DDB1GSPT1IKZF3
SCHEMBL30906248 0.85 CRBN (0.52) CRBNIKZF2DDB1GSPT1IKZF3
SCHEMBL25933315 0.85 CRBN (0.52) CRBNIKZF2DDB1GSPT1IKZF3
SCHEMBL30942356 0.84 CRBN (0.57) CRBNIKZF2DDB1WIZESR1
SCHEMBL22581062 0.84 CRBN (0.57) CRBNIKZF2DDB1WIZESR1
SCHEMBL31129522 0.84 CRBN (0.57) CRBNIKZF2DDB1WIZESR1
SCHEMBL30906214 0.84 CRBN (0.47) CRBNIKZF2DDB1WIZESR1
SCHEMBL30906233 0.84 CRBN (0.56) CRBNIKZF2DDB1WIZESR1
SCHEMBL30942547 0.84 CRBN (0.50) CRBNIKZF2DDB1WIZESR1
SCHEMBL27302571 0.84 CRBN (0.50) CRBNIKZF2DDB1WIZESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598905-A2 CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS University of Florida Research Foundation, Incorporated (US) 2025-08-13 — — EP disclosed
WO-2024077023-A2 CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-04-11 — — WO disclosed
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