Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 7/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.48 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.45 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | WIZ | O95785 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30906217 | 0.93 | IKZF2 (0.55) | IKZF2CRBNGSPT1DDB1CYP2C19 | |
| SCHEMBL30906241 | 0.82 | CRBN (0.47) | IKZF2CRBNGSPT1DDB1CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL30906203 | 0.81 | IKZF2 (0.62) | IKZF2CRBNGSPT1DDB1CYP2C19 | |
| SCHEMBL30906237 | 0.81 | CRBN (0.45) | IKZF2CRBNGSPT1DDB1CYP2C19 | |
| SCHEMBL31033998 | 0.80 | CRBN (0.54) | CRBNDDB1IKZF3 | |
| SCHEMBL31033670 | 0.80 | CRBN (0.54) | CRBNDDB1IKZF3 | |
| SCHEMBL26094346 | 0.80 | CRBN (0.54) | CRBNDDB1IKZF3 | |
| SCHEMBL31034066 | 0.80 | CRBN (0.54) | CRBNDDB1IKZF3 | |
| SCHEMBL26452169 | 0.80 | CRBN (0.54) | CRBNDDB1IKZF3 | |
| SCHEMBL26091676 | 0.80 | CRBN (0.54) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598905-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | University of Florida Research Foundation, Incorporated (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024077023-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-11 | — | — | WO | disclosed |