Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536824 | 0.90 | GPR119 (0.45) | GPR119CNR1ALDH1A1LMNAMAPT | |
| SCHEMBL30159667 | 0.90 | GPR119 (0.45) | GPR119CNR1ALDH1A1LMNAMAPT | |
| SCHEMBL23536714 | 0.87 | HRH1 (0.44) | GPR119ALDH1A1MAPTKDM4ECHRM4 | |
| SCHEMBL31195528 | 0.86 | MAPT (0.54) | GPR119SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL16599993 | 0.86 | MAPT (0.54) | GPR119SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL8349369 | 0.85 | GPR119 (0.50) | GPR119SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL23550059 | 0.85 | GPR119 (0.45) | GPR119CNR1ALDH1A1LMNAMAPT | |
| SCHEMBL30906259 | 0.81 | CRBN (0.50) | SCN9ADDB1CRBN | |
| SCHEMBL30906296 | 0.81 | CRBN (0.50) | SCN9ADDB1CRBN | |
| SCHEMBL29265369 | 0.81 | CRBN (0.50) | SCN9ADDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598905-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | University of Florida Research Foundation, Incorporated (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024077023-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-11 | — | — | WO | disclosed |