Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907574 | 0.74 | PRKCI (0.49) | MKNK1NUDT1RPS6KB1MAPK1 | |
| SCHEMBL29545399 | 0.71 | NOS1 (0.53) | MKNK1CHEK1RAB9ACDK2MAPK1 | |
| SCHEMBL29366050 | 0.71 | NOS1 (0.53) | MKNK1CHEK1LMNARAB9ACDK2 | |
| SCHEMBL16179044 | 0.71 | NOS1 (0.53) | MKNK1CHEK1RAB9ACDK2MAPK1 | |
| SCHEMBL5066090 | 0.71 | NOS1 (0.53) | MKNK1CHEK1LMNARAB9ACDK2 | |
| SCHEMBL30907298 | 0.70 | MAPK1 (0.33) | RETLRRK2AURKACDK9PAK4 | |
| SCHEMBL15577658 | 0.70 | NOS1 (0.53) | XDHRETPI4KALRRK2PI4K2B | |
| SCHEMBL25207869 | 0.69 | ALDH1A1 (0.47) | XDHMKNK1CHEK1LMNATSHR | |
| SCHEMBL30352734 | 0.69 | ALDH1A1 (0.47) | XDHMKNK1CHEK1LMNATSHR | |
| SCHEMBL5569363 | 0.68 | MAPK1 (0.55) | XDHRETPI4KALRRK2PI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |