Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907657 | 0.90 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL30907302 | 0.83 | MKNK2 (0.37) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL30907420 | 0.82 | ABL1 (0.40) | ABL1 | |
| SCHEMBL30907655 | 0.77 | FGFR1 (0.40) | FGFR1SRCNOS1ABL1 | |
| SCHEMBL30907102 | 0.76 | FGFR1 (0.41) | FGFR1SRCNOS1ABL1 | |
| SCHEMBL30907139 | 0.74 | FGFR1 (0.39) | FGFR1SRCNOS1ABL1 | |
| SCHEMBL30907347 | 0.74 | FGFR1 (0.37) | FGFR1SRCNOS1ABL1 | |
| SCHEMBL30907092 | 0.72 | FGFR1 (0.39) | FGFR1SRCNOS1ABL1 | |
| SCHEMBL30907359 | 0.71 | ABL1 (0.42) | FGFR1SRCNOS1ABL1 | |
| SCHEMBL30907529 | 0.69 | ABL1 (0.57) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |