Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ASPH | Q12797 | 1/20 | 0.32 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.32 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907265 | 0.90 | FGFR1 (0.40) | SMN1; SMN2NPSR1LMNAKDM4EALDH1A1 | |
| SCHEMBL30907302 | 0.85 | MKNK2 (0.37) | ABL1 | |
| SCHEMBL30907420 | 0.82 | ABL1 (0.40) | ABL1 | |
| SCHEMBL30780142 | 0.77 | KDM4E (0.45) | LMNAKDM4EALDH1A1HTTMAPT | |
| SCHEMBL27139154 | 0.77 | KDM4E (0.45) | LMNAKDM4EALDH1A1HTTMAPT | |
| SCHEMBL30907430 | 0.76 | ABL1 (0.34) | KDM4EALDH1A1ABL1 | |
| SCHEMBL30907166 | 0.74 | ABL1 (0.34) | SMN1; SMN2ALDH1A1MEN1KMT2AABL1 | |
| SCHEMBL30907397 | 0.74 | NOS1 (0.39) | SMN1; SMN2LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL30907412 | 0.74 | GPBAR1 (0.32) | ABL1 | |
| SCHEMBL30907369 | 0.74 | ABL1 (0.33) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |