Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 5/20 | 0.34 |
| ▸ | KDR | P35968 | 6/20 | 0.33 |
| ▸ | FLT1 | P17948 | 5/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.33 |
| ▸ | FLT4 | P35916 | 5/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907657 | 0.85 | SMN1; SMN2 (0.35) | ABL1 | |
| SCHEMBL30907420 | 0.85 | ABL1 (0.40) | ABL1 | |
| SCHEMBL30907265 | 0.83 | FGFR1 (0.40) | FGFR1SRCABL1PDGFRBPDGFRA | |
| SCHEMBL30907484 | 0.80 | GSK3B (0.36) | FGFR1SRCABL1KDRFLT1 | |
| SCHEMBL30907087 | 0.79 | GSK3B (0.35) | FGFR1SRCABL1KDRFLT1 | |
| SCHEMBL30907378 | 0.76 | GSK3B (0.42) | ABL1GSK3BDYRK1AIRAK4 | |
| SCHEMBL30907294 | 0.74 | ABL1 (0.57) | ABL1GSK3BDYRK1A | |
| SCHEMBL30907084 | 0.74 | GSK3B (0.36) | FGFR1ABL1KDRGSK3BDYRK1A | |
| SCHEMBL30907334 | 0.73 | ABL1 (0.46) | ABL1GSK3BDYRK1A | |
| SCHEMBL30907335 | 0.73 | ABL1 (0.38) | FGFR1SRCABL1KDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |