Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907308 | 0.82 | ABL1 (0.39) | ABL1PDGFRBPDGFRA | |
| SCHEMBL30907290 | 0.79 | ABL1 (0.53) | ABL1 | |
| SCHEMBL30907125 | 0.74 | ABL1 (0.42) | ABL1PDGFRBPDGFRA | |
| SCHEMBL30907424 | 0.74 | ABL1 (0.42) | ABL1PDGFRBPDGFRA | |
| SCHEMBL30885001 | 0.74 | FGFR1 (0.38) | — | |
| SCHEMBL30907414 | 0.73 | GABRA1 (0.36) | ABL1 | |
| SCHEMBL30907372 | 0.70 | ABL1 (0.42) | ABL1 | |
| SCHEMBL30907451 | 0.68 | ABL1 (0.39) | ABL1 | |
| SCHEMBL30884986 | 0.66 | RAB9A (0.34) | ADORA1 | |
| SCHEMBL30907111 | 0.66 | ABL1 (0.43) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |