Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.35 |
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907409 | 0.83 | MAP4K1 (0.36) | ABL1MAP4K1KDM4EHSD17B10 | |
| SCHEMBL30907426 | 0.74 | ABL1 (0.50) | ABL1MAP4K1 | |
| SCHEMBL30907149 | 0.74 | ABL1 (0.50) | ABL1MAP4K1 | |
| SCHEMBL30907326 | 0.74 | ABL1 (0.47) | ABL1MAP4K1 | |
| SCHEMBL30907369 | 0.70 | ABL1 (0.33) | ABL1 | |
| SCHEMBL21240971 | 0.66 | NOS3 (0.40) | KDM4ETSHRHSD17B10 | |
| SCHEMBL30907413 | 0.66 | ABL1 (0.57) | ABL1 | |
| SCHEMBL30907529 | 0.66 | ABL1 (0.57) | ABL1 | |
| SCHEMBL28631402 | 0.65 | MAP4K1 (0.49) | CCNT1CDK9HASPINPIP4K2AMAP4K1 | |
| SCHEMBL29930315 | 0.65 | MAP4K1 (0.49) | CCNT1CDK9HASPINPIP4K2AMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |