Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730661 | 0.84 | KMT2A (0.44) | KMT2ANPSR1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL30908250 | 0.83 | HSD17B10 (0.46) | KMT2ANPSR1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL29911266 | 0.77 | BACE1 (0.46) | KMT2ANPSR1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL3614209 | 0.77 | BACE1 (0.46) | KMT2ANPSR1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL11436664 | 0.76 | TDP1 (0.44) | KMT2ANPSR1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL3835940 | 0.76 | KMT2A (0.62) | KMT2ANPSR1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL8302695 | 0.76 | POLB (0.48) | KMT2ANPSR1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL17221732 | 0.74 | CYP1A2 (0.55) | CYP1A2KDM4ELMNA | |
| SCHEMBL1599287 | 0.74 | NOS1 (0.38) | CYP3A4CYP2C19KDM4EHIF1ACYP4F2 | |
| SCHEMBL12970077 | 0.73 | KMT2A (0.42) | KMT2ANPSR1ALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |