Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | CASP1 | P29466 | 6/20 | 0.50 |
| ▸ | CASP7 | P55210 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31647674 | 0.75 | ALDH1A1 (0.56) | KDM4EALDH1A1SMN1; SMN2MAPTCASP1 | |
| SCHEMBL6948388 | 0.75 | ALDH1A1 (0.40) | KDM4EALDH1A1SMN1; SMN2MAPTCASP1 | |
| SCHEMBL16019317 | 0.72 | SMN1; SMN2 (0.60) | KDM4EALDH1A1SMN1; SMN2MAPTCASP1 | |
| SCHEMBL25073970 | 0.69 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL30471680 | 0.69 | SMN1; SMN2 (0.60) | KDM4EALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL16019318 | 0.69 | SMN1; SMN2 (0.93) | KDM4EALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL23793117 | 0.69 | SMN1; SMN2 (0.60) | KDM4EALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL29375167 | 0.69 | SMN1; SMN2 (0.93) | KDM4EALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL15116256 | 0.69 | SMN1; SMN2 (0.65) | KDM4EALDH1A1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL4107462 | 0.69 | SMN1; SMN2 (0.65) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |