Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457873 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTPOLBHPGDKDM4E | |
| SCHEMBL7513902 | 0.80 | SMN1; SMN2 (0.58) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL30908489 | 0.78 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HPGDLMNAKDM4E | |
| SCHEMBL15520734 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL29777618 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL7451772 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL29159122 | 0.75 | TDP1 (0.40) | MAPTPOLBHPGDKDM4EKMT2A | |
| SCHEMBL7455786 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL20023765 | 0.74 | TDP1 (0.42) | ALDH1A1POLBSMN1; SMN2HPGDKDM4E | |
| SCHEMBL26120935 | 0.74 | POLB (0.40) | ALDH1A1MAPTPOLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |