Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15520734 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL7451066 | 0.78 | LMNA (0.46) | ALDH1A1KMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL30908417 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KMT2ASMN1; SMN2LMNAHPGD | |
| SCHEMBL7516717 | 0.77 | LMNA (0.47) | ALDH1A1KMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL32683716 | 0.76 | KMT2A (0.47) | ALDH1A1KMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL1431212 | 0.75 | PDE4B (0.39) | ALDH1A1KMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL24828443 | 0.73 | TSHR (0.45) | ALDH1A1KMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL29159108 | 0.72 | ALDH1A1 (0.36) | ALDH1A1KMT2ATSHRMEN1LMNA | |
| SCHEMBL4227041 | 0.71 | KDM4E (0.48) | ALDH1A1KMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL1412462 | 0.71 | MAPK1 (0.39) | ALDH1A1KMT2ATSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |