SCHEMBL30908441

SCHEMBL30908441

N#Cc1cc(C(=O)O)cnc1C1CC1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
XDH P47989 12/20 0.46
HCAR3 P49019 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30908493 0.82 MAPK1 (0.40) XDHALDH1A1HPGD
SCHEMBL18987911 0.77 MGAM (0.43) XDH
SCHEMBL3374054 0.77 HCAR2 (0.42) HCAR3ALDH1A1
SCHEMBL30973945 0.76 XDH (0.54) XDHALDH1A1HPGD
SCHEMBL27416286 0.76 XDH (0.54) XDHALDH1A1HPGD
SCHEMBL11184877 0.75 XDH (0.49) XDHALDH1A1HPGD
SCHEMBL31030191 0.75 ALDH1A1 (0.51) XDHALDH1A1HPGD
SCHEMBL29877405 0.75 XDH (0.49) XDHALDH1A1HPGD
SCHEMBL2227107 0.75 XDH (0.49) XDHALDH1A1HPGD
SCHEMBL27466139 0.75 ALDH1A1 (0.51) XDHALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024074611-A1 PRMT5 INHIBITORS Ryvu Therapeutics S.A. (PL) 2024-04-11 WO disclosed