Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 6/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 2/20 | 0.32 |
| ▸ | EDNRA | P25101 | 2/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817853 | 1.00 | GBA1 (0.39) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL15240230 | 0.83 | ADRA2A (0.38) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL1820710 | 0.78 | GBA1 (0.37) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL15001189 | 0.78 | PDE10A (0.43) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL152558 | 0.78 | PDE10A (0.43) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL15001191 | 0.78 | PDE10A (0.43) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL29926723 | 0.77 | GBA1 (0.41) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL681100 | 0.77 | GBA1 (0.41) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL15651900 | 0.77 | KDM4E (0.37) | KDM4EADRA2AADRA2BADRA2CRAB9A | |
| SCHEMBL3396791 | 0.77 | ALDH1A1 (0.37) | GBA1ALDH1A1KDM4EADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |