Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908383 | 0.88 | LCK (0.43) | SCN9ACYP17A1GSK3BDYRK1AMAPK14 | |
| SCHEMBL30908382 | 0.88 | LCK (0.43) | SCN9ACYP17A1GSK3BDYRK1AMAPK14 | |
| SCHEMBL30908492 | 0.84 | TOP2A (0.41) | SCN9ACYP17A1GSK3BDYRK1AMAPK14 | |
| SCHEMBL30908325 | 0.81 | NPC1 (0.45) | SCN9AGSK3BDYRK1ALCKMAPT | |
| SCHEMBL16930398 | 0.81 | NPC1 (0.44) | SCN9AMTNR1AMTNR1BMAPTNPC1 | |
| SCHEMBL9382249 | 0.80 | SCN9A (0.41) | SCN9ACYP17A1AKT1TOP2ATOP2B | |
| SCHEMBL540467 | 0.79 | NAMPT (0.49) | SCN9ACYP17A1GSK3BDYRK1AAKT1 | |
| SCHEMBL167992 | 0.77 | IGF1R (0.47) | SCN9ACYP17A1GSK3BDYRK1AAKT1 | |
| SCHEMBL30908271 | 0.77 | PTPN1 (0.36) | SCN9AAKT1TOP2ATOP2BNPC1 | |
| SCHEMBL12567166 | 0.76 | SORT1 (0.43) | GSK3BDYRK1ALCKHDAC1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |