Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TSPO | P30536 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908442 | 0.93 | AURKA (0.37) | TOP2ATOP2BAKT1SCN9ASMN1; SMN2 | |
| SCHEMBL30908483 | 0.93 | TSPO (0.39) | TOP2ATOP2BAKT1SCN9ASMN1; SMN2 | |
| SCHEMBL30908391 | 0.88 | TOP2A (0.35) | PTPN1TOP2ATOP2BAKT1SCN9A | |
| SCHEMBL30908158 | 0.87 | METAP1 (0.39) | TOP2ATOP2BAKT1SCN9A | |
| SCHEMBL30908503 | 0.86 | NPC1 (0.35) | TOP2ATOP2BSCN9ANPC1RAB9A | |
| SCHEMBL30908423 | 0.86 | SCN9A (0.41) | TOP2ATOP2BAKT1SCN9AALDH1A1 | |
| SCHEMBL30908418 | 0.86 | SCN9A (0.41) | TOP2ATOP2BAKT1SCN9AALDH1A1 | |
| SCHEMBL30908405 | 0.83 | HDAC1 (0.35) | TOP2ATOP2BSCN9A | |
| SCHEMBL30908217 | 0.83 | GSK3B (0.37) | TOP2ATOP2BSCN9AACSS2 | |
| SCHEMBL30908222 | 0.83 | METAP1 (0.38) | TOP2ATOP2BSCN9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |