Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 7/20 | 0.39 |
| ▸ | NOS3 | P29474 | 6/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534945 | 0.87 | CYP3A4 (0.76) | KDM4ECYP3A4CYP2C19HIF1AHSD17B10 | |
| SCHEMBL18325649 | 0.83 | POLB (0.56) | KDM4EHSD17B10POLBMEN1KMT2A | |
| SCHEMBL5434270 | 0.77 | KDM4E (0.50) | KDM4ECYP3A4CYP2C19HIF1AHSD17B10 | |
| SCHEMBL3420261 | 0.77 | POLB (0.52) | KDM4ECYP3A4CYP2C19HIF1APOLB | |
| SCHEMBL8936155 | 0.77 | POLB (0.72) | KDM4ECYP3A4CYP2C19HIF1AHSD17B10 | |
| SCHEMBL5518584 | 0.77 | MAPT (0.51) | KDM4ECYP3A4CYP2C19HIF1AHSD17B10 | |
| SCHEMBL1600117 | 0.74 | KDM4E (0.49) | KDM4ECYP3A4CYP2C19HIF1AHSD17B10 | |
| SCHEMBL7424524 | 0.74 | CYP2C19 (0.49) | KDM4ECYP3A4CYP2C19HIF1APOLB | |
| SCHEMBL3060777 | 0.74 | KDM4E (0.49) | KDM4ECYP3A4CYP2C19HIF1AHSD17B10 | |
| SCHEMBL5437258 | 0.74 | KDM4E (0.49) | KDM4ECYP3A4CYP2C19HIF1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |