Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.45 |
| ▸ | FEN1 | P39748 | 4/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439407 | 1.00 | GAA (0.58) | GAACA9CA12CA1CA2 | |
| SCHEMBL4066986 | 0.83 | GAA (0.54) | GAACA9CA12CA1CA2 | |
| SCHEMBL10877565 | 0.83 | ALDH1A1 (0.47) | GAACA9CA12CA1CA2 | |
| SCHEMBL7212515 | 0.82 | CYP3A4 (0.48) | GAACA9CA12CA1CA2 | |
| SCHEMBL7235244 | 0.80 | GAA (0.50) | GAACA9CA12CA1CA2 | |
| SCHEMBL29900497 | 0.80 | TTR (0.59) | CA2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9355856 | 0.80 | MCOLN3 (0.58) | GAACA9CA12CA1CA2 | |
| SCHEMBL12086969 | 0.80 | ALDH1A1 (0.45) | GAACA9CA12CA1CA2 | |
| SCHEMBL7913374 | 0.80 | TTR (0.59) | CA2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL13395312 | 0.80 | GAA (0.50) | GAACA9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |