Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | NSD2 | O96028 | 9/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29900497 | 1.00 | TTR (0.59) | TTRNSD2CA2TDP1HTT | |
| SCHEMBL9276192 | 0.89 | CHEK1 (0.48) | TTRNSD2CA2TDP1HTT | |
| SCHEMBL29212099 | 0.81 | CYP1A2 (0.71) | NSD2CA2TDP1HTTCYP1A2 | |
| SCHEMBL10877565 | 0.81 | ALDH1A1 (0.47) | TTRNSD2CA2HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL10867384 | 0.80 | MCL1 (0.47) | TTRNSD2CA2TDP1ALDH1A1 | |
| SCHEMBL30908488 | 0.80 | GAA (0.58) | CA2HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL1439407 | 0.80 | GAA (0.58) | CA2HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7212515 | 0.79 | CYP3A4 (0.48) | TTRNSD2CA2HTTALDH1A1 | |
| SCHEMBL9927438 | 0.79 | TTR (0.66) | TTRNSD2CA2TDP1ALDH1A1 | |
| SCHEMBL13788915 | 0.78 | TDP1 (0.54) | TTRNSD2CA2TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001010890-A2 | PROCESS OF SYNTHESIS OF FLUORESCENT PROTEASE SUBSTRATES | CHEMRX ADVANCED TECHNOLOGIES, INC. (US) | 2001-02-15 | — | — | WO | claimed |
| US-20240262792-A1 | USP30 INHIBITORS AND USES THEREOF | VINCERE BIOSCIENCES, INC. | 2024-08-08 | — | — | US | disclosed |
| US-11845724-B2 | USP30 inhibitors and uses thereof | VINCERE BIOSCIENCES, INC. (US) | 2023-12-19 | — | — | US | disclosed |
| US-20220315531-A1 | USP30 INHIBITORS AND USES THEREOF | VINCERE BIOSCIENCES, INC. | 2022-10-06 | — | — | US | disclosed |
| EP-4028385-A1 | USP30 INHIBITORS AND USES THEREOF | Vincere Biosciences, Inc. (US) | 2022-07-20 | — | — | EP | disclosed |
| WO-2021050992-A1 | USP30 INHIBITORS AND USES THEREOF | VINCERE BIOSCIENCES, INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| WO-2021050992-A1 | USP30 INHIBITORS AND USES THEREOF | VINCERE BIOSCIENCES, INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| US-20090186829-A1 | Nitrosation-Inducible Inhibitors Biological Macromolecules | NEW YORK UNIVERSITY (US) | 2009-07-23 | — | — | US | disclosed |
| US-20090186829-A1 | Nitrosation-Inducible Inhibitors Biological Macromolecules | NEW YORK UNIVERSITY (US) | 2009-07-23 | — | — | US | disclosed |
| WO-2001010890-A2 | PROCESS OF SYNTHESIS OF FLUORESCENT PROTEASE SUBSTRATES | CHEMRX ADVANCED TECHNOLOGIES, INC. (US) | 2001-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11845724-B2 | USP30 inhibitors and uses thereof | USP30, USP28, USP1 | TTR 3779/4885NSD2 1033/4885CA2 4601/4885 |
| US-20220315531-A1 | USP30 INHIBITORS AND USES THEREOF | USP30, USP28, USP1 | TTR 3779/4885NSD2 1033/4885CA2 4601/4885 |
| US-20240262792-A1 | USP30 INHIBITORS AND USES THEREOF | USP30, USP28, USP1 | TTR 3779/4885NSD2 1033/4885CA2 4601/4885 |
| US-20090186829-A1 | Nitrosation-Inducible Inhibitors Biological Macromolecules | NOS2, NOS1, NOS3 | TTR 790/4885NSD2 1919/4885CA2 3421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.