Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16703224 | 0.88 | HCAR2 (0.50) | HCAR2RXRARXRBRXRGRARB | |
| SCHEMBL31704833 | 0.85 | LRRK2 (0.40) | HDAC3HDAC1HDAC2HDAC6HSD17B10 | |
| SCHEMBL23146241 | 0.85 | HCAR2 (0.47) | HCAR2RXRARXRBRXRGRARB | |
| Lithium Ion SCHEMBL31705970 | 0.84 | HDAC3 (0.32) | HDAC3HDAC1HDAC2HDAC6CHRM4 | |
| Lithium Ion SCHEMBL31704521 | 0.84 | HDAC3 (0.32) | HDAC3HDAC1HDAC2HDAC6CHRM4 | |
| SCHEMBL628736 | 0.82 | HCAR2 (0.39) | HCAR2RXRARXRBRXRGPOLB | |
| SCHEMBL30908652 | 0.79 | HCRTR2 (0.48) | HTTL3MBTL1PIK3CAHSD17B10 | |
| SCHEMBL31705644 | 0.78 | NAMPT (0.39) | HCAR2MLYCDHTTCHRM4ALDH1A1 | |
| SCHEMBL4781839 | 0.77 | GSK3B (0.36) | KDM4EMLYCDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL2406553 | 0.77 | HCAR2 (0.46) | HCAR2RXRARXRBRXRGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |