Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL31704521 | 1.00 | HDAC3 (0.32) | HDAC3HDAC1HDAC2HDAC6CHRM4 | |
| SCHEMBL30908520 | 0.84 | HCAR2 (0.43) | HDAC3HDAC1HDAC2HDAC6CHRM4 | |
| SCHEMBL31704833 | 0.79 | LRRK2 (0.40) | HDAC3HDAC1HDAC2HDAC6 | |
| Lithium Ion SCHEMBL31705486 | 0.79 | NAMPT (0.37) | CHRM4 | |
| Lithium Ion SCHEMBL31706602 | 0.79 | NAMPT (0.37) | CHRM4 | |
| Lithium Ion SCHEMBL15376216 | 0.77 | MLYCD (0.56) | — | |
| SCHEMBL30908652 | 0.76 | HCRTR2 (0.48) | — | |
| SCHEMBL16703224 | 0.72 | HCAR2 (0.50) | — | |
| SCHEMBL16426790 | 0.70 | CHRM4 (0.35) | HDAC3HDAC1HDAC2HDAC6CHRM4 | |
| SCHEMBL21066432 | 0.70 | GSK3B (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |