SCHEMBL3090860

SCHEMBL3090860

CCCCCC(C)(C)c1cc(Cc2cc(C(C)(C)C)cc(C(C)(C)C)c2O)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 11/20 0.37
CNR1 P21554 11/20 0.37
GPR18 Q14330 3/20 0.37
GPR55 Q9Y2T6 3/20 0.37
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
HSPA5 P11021 2/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
NR5A2 O00482 1/20 0.34
NR5A1 Q13285 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
XBP1 P17861 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3077136 0.96 CNR1 (0.37) CNR2CNR1GPR18GPR55NPC1
SCHEMBL3072179 0.93 CNR1 (0.39) CNR2CNR1GPR18GPR55NPC1
SCHEMBL551721 0.92 HSPA5 (0.45) CNR2CNR1GPR18GPR55CYP2C9
SCHEMBL258641 0.92 CNR1 (0.41) CNR2CNR1GPR18GPR55NPC1
SCHEMBL3078801 0.90 CNR1 (0.37) CNR2CNR1GPR18GPR55NPC1
SCHEMBL3077803 0.89 HSPA5 (0.42) CYP2C9CYP2C19CYP1A2CYP3A4TSHR
SCHEMBL3067221 0.87 NPC1 (0.43) CNR2CNR1GPR18GPR55CYP2C9
Bisoctrizole SCHEMBL5994398 0.87 CNR2 (0.39) CNR2CNR1GPR18GPR55NPC1
SCHEMBL3090854 0.86 NPC1 (0.37) CYP2C9CYP2C19CYP1A2CYP3A4TSHR
SCHEMBL3075839 0.85 NPC1 (0.38) CYP2C9CYP2C19CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5932142-A REACTING 2-HYDROXYPHENYLBENZOTRIAZOLE AND 2,4-DISUBSTITUTED PHENOL WITH AN ALDEHYDE JOHOKU CHEMICAL CO., LTD. (JP) 1999-08-03 US claimed
US-8808951-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2014-08-19 US disclosed
EP-1816522-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY HODOGAYA CHEMICAL CO LTD (JP) 2013-12-25 EP disclosed
US-20130266343-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY HODOGAYA CHEMICAL CO LTD (JP) 2013-10-10 US disclosed
EP-2485092-A1 Electrophotographic photosensitive body Hodogaya Chemical Co., Ltd. (JP) 2012-08-08 EP disclosed
US-20100291480-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY HODOGAYA CHEMICAL CO., LTD. (JP) 2010-11-18 US disclosed
US-7790342-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2010-09-07 US disclosed
US-20090226830-A1 Using in combination a p-terphenyl compound, N-N'-diphenyl-N,N'-di-p- tolyl-4,4''-diamino-p-terphenyl, as charge transport agent and a polycarbonate homo- and copolymer of bisphenol A or analogues as binder; providing an high photosensitive, improved residual potential and high durability HODOGAYA CHEMICAL CO., LTD. (JP) 2009-09-10 US disclosed
EP-1816522-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Hodogaya Chemical Co., Ltd. (JP) 2007-08-08 EP disclosed
EP-1077246-B1 Use of benzotriazolyl-alkylene bisphenol compounds as antioxidants for organic materials JOHOKU CHEMICAL CO LTD (JP) 2005-01-26 EP disclosed
US-6790574-B2 HAVING PHOTOSENSITIVE LAYER CONTAINING AS A CHARGE TRANSPORTING MATERIAL AT LEAST ONE INDANE COMPOUND AND AT LEAST ONE POLYCARBONATE RESIN AND/OR AN ORGANIC ADDITIVE CONTAINING NITROGEN OXYGEN, PHOSPHORUS OR SULFUR HODOGAYA CHEMICAL CO., LTD. (JP) 2004-09-14 US disclosed
US-20030203298-A1 Electrophotographic photoreceptor HODOGAYA CHEMICAL CO., LTD. (JP) 2003-10-30 US disclosed
EP-0847997-B1 Process for the preparation of Benzotriazolylalkylene bisphenol compounds JOHOKU CHEMICAL CO LTD (JP) 2002-02-06 EP disclosed
EP-1095956-A2 Thermoset Polyurethane resin and method for the production thereof Mitsui Chemicals, Inc. (JP) 2001-05-02 EP disclosed
EP-1077246-A2 Use of benzotriazolyl-alkylene bisphenol compounds as antioxidants for organic materials Johoku Chemical Co., Ltd. (JP) 2001-02-21 EP disclosed
US-5932142-A REACTING 2-HYDROXYPHENYLBENZOTRIAZOLE AND 2,4-DISUBSTITUTED PHENOL WITH AN ALDEHYDE JOHOKU CHEMICAL CO., LTD. (JP) 1999-08-03 US disclosed
EP-0847997-A1 Benzotriazolyl-alkylene bisphenol compounds, process for their preparation, and stabilized organic materials containing them Johoku Chemical Co., Ltd. (JP) 1998-06-17 EP disclosed