Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 15/20 | 0.57 |
| ▸ | HTR1D | P28221 | 9/20 | 0.57 |
| ▸ | HTR1B | P28222 | 7/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR1E | P28566 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005987 | 1.00 | HTR1F (0.57) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7011040 | 0.89 | HTR1F (0.57) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7010396 | 0.83 | HTR1F (0.59) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL30909021 | 0.83 | HTR1F (0.59) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7015495 | 0.80 | HTR1F (0.72) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL30909195 | 0.79 | HTR1F (0.55) | HTR1FHTR1DHTR1BADRA1DSLC6A4 | |
| SCHEMBL7009821 | 0.75 | HTR1F (0.75) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL30908801 | 0.74 | KDM4E (0.52) | HTR1FHTR1AHTR2AHTR2CHTR6 | |
| SCHEMBL8819815 | 0.74 | SLC6A4 (0.56) | HTR1AHTR2AHTR6ADRA1DSLC6A4 | |
| SCHEMBL7013589 | 0.73 | HTR1F (0.80) | HTR1FHTR1DHTR1BHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125645-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ LP (CA) | 2026-05-07 | — | — | US | disclosed |
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125645-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | HTR1F, HTR1A, HTR1D | HTR1F 1/4885HTR1D 3/4885HTR1B 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.