Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 11/20 | 0.38 |
| ▸ | HTR2A | P28223 | 10/20 | 0.38 |
| ▸ | DRD3 | P35462 | 10/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385667 | 1.00 | F2R (0.40) | F2RHRH3DRD2HTR2ADRD3 | |
| SCHEMBL30909176 | 0.93 | DRD2 (0.38) | F2RHRH3DRD2HTR2ADRD3 | |
| SCHEMBL8383620 | 0.93 | DRD2 (0.38) | F2RHRH3DRD2HTR2ADRD3 | |
| SCHEMBL30909206 | 0.92 | DRD2 (0.36) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8386459 | 0.92 | DRD2 (0.36) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8382998 | 0.88 | RAB9A (0.43) | DRD2HTR2ADRD3MAPTNPC1 | |
| SCHEMBL30909023 | 0.88 | RAB9A (0.43) | DRD2HTR2ADRD3MAPTNPC1 | |
| SCHEMBL8382621 | 0.86 | HTR2A (0.41) | HRH3DRD2HTR2ADRD3KMT2A | |
| SCHEMBL8385565 | 0.86 | HTR2A (0.44) | HRH3DRD2HTR2ADRD3MAPT | |
| SCHEMBL30908902 | 0.86 | HTR2A (0.44) | HRH3DRD2HTR2ADRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |