Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NOS3 | P29474 | 2/20 | 0.51 |
| ▸ | NOS1 | P29475 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477358 | 1.00 | MAPT (0.51) | MAPTLMNANOS3NOS1TP53 | |
| SCHEMBL7487596 | 0.92 | MAPT (0.51) | MAPTLMNANOS3NOS1TP53 | |
| SCHEMBL7481114 | 0.91 | LMNA (0.56) | MAPTLMNANOS3NOS1TP53 | |
| SCHEMBL7480553 | 0.89 | MAPT (0.49) | MAPTLMNANOS3NOS1TP53 | |
| SCHEMBL30908919 | 0.89 | MAPT (0.49) | MAPTLMNANOS3NOS1TP53 | |
| SCHEMBL7479602 | 0.88 | LMNA (0.57) | MAPTLMNANOS3NOS1TP53 | |
| SCHEMBL7477371 | 0.88 | NOS3 (0.63) | MAPTLMNANOS3NOS1TP53 | |
| SCHEMBL7484079 | 0.86 | NOS3 (0.53) | MAPTLMNANOS3NOS1TP53 | |
| SCHEMBL7481112 | 0.86 | MAPT (0.49) | MAPTLMNANOS3NOS1TP53 | |
| SCHEMBL30908772 | 0.86 | MAPT (0.49) | MAPTLMNANOS3NOS1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |