Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | HTR1B | P28222 | 3/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962339 | 1.00 | HTR1F (0.49) | HTR1FALDH1A1LMNAPDE4APDE4B | |
| SCHEMBL6962343 | 0.84 | ALDH1A1 (0.48) | HTR1FALDH1A1LMNAPDE4APDE4B | |
| Phosphoric Acid SCHEMBL6965225 | 0.83 | MAPKAPK2 (0.56) | HTR1FALDH1A1LMNAPDE4APDE4B | |
| SCHEMBL8109238 | 0.80 | HTR1F (0.57) | HTR1FALDH1A1LMNAMAPKAPK2KMT2A | |
| SCHEMBL6964601 | 0.80 | HTR1F (0.54) | HTR1FALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7662553 | 0.76 | HTR1F (0.81) | HTR1FALDH1A1LMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6963197 | 0.76 | HTR1F (0.68) | HTR1FALDH1A1LMNAMAPKAPK2KMT2A | |
| SCHEMBL30908928 | 0.76 | HTR1F (0.51) | HTR1FALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8101018 | 0.76 | HTR1F (0.51) | HTR1FALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8101122 | 0.76 | HTR1F (0.55) | HTR1FALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |