Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721209 | 1.00 | MAPT (0.46) | MAPTKDM4EHSD17B10CASP1CASP7 | |
| SCHEMBL8386469 | 0.90 | NPC1 (0.45) | MAPTKDM4EHSD17B10CASP1CASP7 | |
| SCHEMBL30908982 | 0.90 | NPC1 (0.45) | MAPTKDM4EHSD17B10CASP1CASP7 | |
| SCHEMBL30908915 | 0.86 | RAB9A (0.38) | MAPTKDM4EHSD17B10CASP1CASP7 | |
| SCHEMBL8723998 | 0.86 | RAB9A (0.38) | MAPTKDM4EHSD17B10CASP1CASP7 | |
| SCHEMBL8720781 | 0.85 | MAPT (0.45) | MAPTKDM4EHSD17B10CASP1CASP7 | |
| SCHEMBL8387333 | 0.80 | TP53 (0.41) | MAPTKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL8723969 | 0.79 | MTNR1A (0.34) | POLB | |
| SCHEMBL8721072 | 0.79 | MTNR1A (0.34) | ALDH1A1TP53MAPK1POLBMEN1 | |
| SCHEMBL30909058 | 0.79 | MTNR1A (0.34) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |