Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 20/20 | 0.52 |
| ▸ | HTR1B | P28222 | 17/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR1F | P30939 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480628 | 1.00 | HTR1D (0.52) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL30908768 | 0.85 | SLC6A4 (0.44) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL8383651 | 0.85 | SLC6A4 (0.44) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL7485431 | 0.84 | HTR1D (0.65) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL8547830 | 0.83 | DRD2 (0.52) | DRD2 | |
| SCHEMBL7484678 | 0.80 | HTR1D (0.73) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL7480742 | 0.77 | HTR1D (0.61) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL7483902 | 0.77 | HTR1D (0.51) | HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL7485421 | 0.77 | HTR1D (0.55) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL7480617 | 0.76 | CCR2 (0.61) | HTR1DHTR1BCHRM2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |